Fig. 1
From: MiRNAs as potential therapeutic targets and biomarkers for non-traumatic intracerebral hemorrhage
MicroRNA (miRNA) biogenesis. MiRNA biogenesis is well studied and described in detail. It is a multi-step process regulated by several enzymes where the formation of mature miRNA proceeds in two ways, canonical and non-canonical. Note: pri-miRNA, primary microRNA; pre-miRNA, precursor microRNA; RISC, RNA-induced silencing complex; mRNA, messenger RNA; Ago, Argounaute; TRBP, Transactivation response element RNA-binding protein